IDENTIFICATION OF AN IRON METABOLISM-RELATED LNCRNA SIGNATURE FOR PREDICTING OSTEOSARCOMA SURVIVAL AND IMMUNE LANDSCAPE

Identification of an Iron Metabolism-Related lncRNA Signature for Predicting Osteosarcoma Survival and Immune Landscape

Background: Long noncoding RNAs (lncRNAs) act as epigenetic regulators in the process of ferroptosis and iron metabolism.This study aimed to identify an iron metabolism-related lncRNA signature to predict osteosarcoma (OS) survival and the immune landscape.Methods: RNA-sequencing data and clinical information were obtained from the TARGET dataset.U

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Evaluation of Sinensetin Derived From Flavonoids-Rich Orthosiphon Stamineus as a New Radiosensitizer in MDA-MB-231 and T47D as Breast Cancer Cell Lines

Introduction: Breast cancer is one of the most prevalent diseases around the MCB world.Breast cancer patients treated with radiation may face Side effects as well as cancer recurrence.Some polyphenols exhibit antioxidant effects.Citrus and Orthosiphon Stamineus have source of methylated flavone called Sinensetin (SIN).In this research, we designati

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Key competences and plurilingual education in the Valencian Region (Spain): A curricular analysis of Primary Education

The purpose of this work is to study the level of transversality of key competences in Primary Education in the Valencian Community.To this end, an analysis of the Decree 108/2014 currently in effect will be carried out, along with determining the frequency with which each competence is worked on during this stage of education.The data obtained wil

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Extracellular Vesicles from Mesenchymal Stem Cells: Potential as Therapeutics in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Background/Objectives: Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by the accumulation of triglycerides within hepatocytes, which can progress to more severe conditions, such as metabolic dysfunction-associated steatohepatitis (MASH), which may include progressive fibrosis, leading to cirrhosis, cancer, and dea

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